DO ASPIRIN CAN PREVENT CANCER?
A new study suggests that it is true that aspirin can prevent some forms of cancer.
Cancer is one of the fatal diseases and its prevalence is increasing every year exponentially worldwide. It can be prevented by healthy and clean lifestyles and by proper predictive tests to prevent it to occur.
A new study has suggested that a very low dose of aspirin taken periodically prevents the formation of cancer cells. This has been explained below.
In the year 2015 The United States Preventive Services Task Force suggested that daily use of a small dose of aspirin can prevent stroke and colorectal cancer.
The above theory has been confirmed by a research team from Oregon Health and Science University in collaboration with Oregon State University and the result is published in AJP Cell Physiology.
The study illustrates that aspirin indirectly inhibits the oncoprotein which causes the formation of cancer cells.
The effect is due to its anti-platelet activity rather than its direct action on the tumor cells.
Platelets are minute blood cells that in a healthy body prevent blood loss by forming small clots to check bleedings whenever necessary.
But it seems that the platelets also cause an increase in the level of a certain kind of blood protein which stimulates the formation of cancer cells. The oncoprotein is called as cMYC.
The actual metabolic function of the cMYC is regulating at least 15% of gene expression, cell formation and death, and total comprehensive cell metabolism. Hence overexpression of the genes in the cells stimulated by cMYC may trigger irregularity in cell multiplication and metabolism.
This will eventually lead to cancer.
In general the cancer cells lives in a hostile atmosphere as our body's natural immunity system tries attack to destroy them But the blood platelets give protection to them by increasing the cMYC levels in the blood. Aspirin in low doses can prevent and dismay the protection by acting on the platelets.
This is the first time that a study has shown the important role of the platelets regulating the gene expressions in cancer cells.
he researchers proved that almost a third of colorectal cancer and about 42% pancreatic cancer has the overexpression of cMYC.
Fortunately it has been proved that a low dose aspirin acts similarly and gives almost an equal superb effect as in high dose. Hence aspirin in its low dose can give a beneficial effect in preventing the cancer cells to proliferate and metastasize.
Disclaimer
I have prepared the above article based on news surfaced in the media. But I say that read the above article for an informative purpose only to have a theory of drugs. But usage of any medicine should be under medical supervision.
The question is why the researchers highlighted their object of the research by the branded name Aspirin of BAYER and not by the generic name Acetylsalicylic acid.?
Perhaps even if the research might have been sponsored by Bayer, the researchers conducted their research as a part of Aspirin's promotion.
One thing we should keep in our mind that acetylsalicylic acid (Aspirin) the generic drug is a salicylic acid derivative and irreversibly inhibits prostaglandin synthesis by the irreversible inhibition of the cyclooxygenase enzyme on prolonged use. This may lead to ulceration, kidney problems, and many more things.
Aspirin may exacerbate the condition of gout by elevating the uric acid level in the blood.
The research further says that prolonged use of aspirin is needed as an anti-cancer drug.
Hence it is still too early to start recommending to patients, say experts.
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